Cardiff University MEG lab

Cardiff University MEG lab

Research topics

Since the opening of the lab back in 2006, MEG research in Cardiff has focused on the origin and role of cortical oscillatory signals, with particular emphasis on gamma oscillations in the visual system. Typically, we study oscillations with simple, well-established sensory-motor tasks, in the context of both normal and pathological brain function.

Two key aspects of our approach to human neuroscience are the incorporation of animal models in the generation of our experimental hypotheses and the study of the relationship between MEG and fMRI signals. We adopt systematic pharmacological manipulations as a tool to probe the neurophysiological mechanisms generating frequency-specific oscillations in the sensory-motor system.

Importantly, understanding the origin of these electrophysiological signals bears the potential for both the development of markers of disease and for the advancement of drug discovery. In this perspective, our research efforts extend to the analysis of neuronal signals at the network level. This ranges from the fine-grained models of neuronal function in cortical microcircuits, implemented with dynamic causal modelling (DCM), to the analysis of oscillatory signals originating from distant cortical regions at the whole-brain level, using both functional and effective connectivity analysis methods.

Research facilities and equipment

The MEG lab at Cardiff University is equipped with a 275 channel CTF axial gradiometer system. The MEG is located in a large magnetically shielded room (5×4 m), which is particularly well-suited to clinical and pharmacological studies. Vision studies are performed using a state-of-the-art PROPixx projection system (VPixx) and an EyeLink 1000 Plus eye-tracker (SR Research).

A description of the MEG lab setup is available at the following link: http://sites.cardiff.ac.uk/cubric/facilities/meg.

Location

The MEG laboratory at Cardiff University is part of the new CUBRIC Building, which opened in March 2016. More information about CUBRIC is available at the following link: http://sites.cardiff.ac.uk/cubric/.

People

Cardiff University MEG team

Head

Prof Krish Singh
Head of Human Electrophysiology

Academic Investigators

Prof Derek Jones
CUBRIC Director

Prof David Linden
Head of Clinical Neuroimaging Research

Prof Richard Wise
Head of Magnetic Resonance Imaging

Dr Aline Bompas
Lecturer

Dr Khalid Hamandi
Consultant Neurologist

Dr David McGonigle
Lecturer

Dr Neeraj Saxena
Clinical Senior Lecturer

Dr James Walters
Clinical Senior Lecturer

Dr Jiaxiang Zhang
Senior Lecturer

Core Staff

Dr Gavin Perry
MEG Lab Manager

Sonya Foley
Scientific Support Officer

Martin Stuart
Senior Technician

Post-Doctoral Researchers & Fellows

Dr Christopher Allen
Research Fellow

Dr Stavros Dimitriadis
Research Fellow

Dr Johanne Doherty
Clinical Fellow / PhD Student

Dr Mark Drakesmith
Research Associate

Dr Loes Koelewijn
Research Associate

Dr Lorenzo Magazzini
Research Associate

Dr Holly Rossiter
Research Fellow

Dr Bethany Routley
Research Associate

Dr Alexander Shaw
Research Fellow

Dr Gemma Williams
Clinical Fellow / PhD Student

PhD Students & Research Assistants

Phoebe Asquith
PhD Student

Laura Bloomfield
PhD Student

Diana Dima
PhD Student

Sophie Esterer
PhD Student

Megan Godfrey
PhD Student

Emily Lambe
Research Assistant

Rachael Stickland
PhD Student

Maciej Szul
PhD Student

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